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May 31, 2007

Army Researchers Gave Soldiers Drugs, Book Says

Army Researchers Gave Soldiers Drugs, Book Says

Army researchers studying chemical weapons administered a variety of illicit drugs to volunteer soldiers over nearly a 20-year period, according to a new book.

May 30, 2007

Abstinence and moderate use goals in the treatment of marijuana dependence

Abstinence and moderate use goals in the treatment of marijuana dependence

Marijuana users approaching and abstinence-orientated treatment varied in the extent to which they were actively seeking abstinence as the outcome.

May 25, 2007

Smoking, Mood Regulation, and Personality: An Event-Sampling Exploration of Potential Models and Moderation

Smoking, Mood Regulation, and Personality: An Event-Sampling Exploration of Potential Models and Moderation

Journal of Personality Volume 75, Issue 3, Page 451-478, Jun 2007.
ABSTRACT The aim of the present study was to test potential models of smoking-related changes in mood and how these are moderated by personality (behavioral activation and inhibition systems). Three models yielding distinct predictions regarding mood cha...

May 24, 2007

When parents use drugs: key findings from qualitative research on parenting and children in Iran

When parents use drugs: key findings from qualitative research on parenting and children in Iran

Child & Family Social Work Volume 12, Issue 2, Page 113-122, May 2007.
ABSTRACT This paper reports on the finding of a grounded theory study on drug dependency and parenting in Iran. This study is qualitative in nature; data were obtained through semi-structured interviews. The grounded theory method was used to guide the an...

Introduction to Addictive Behaviours

Introduction to Addictive Behaviours

Addiction Volume 102, Issue 5, Page 831-831, May 2007.

May 23, 2007

African-American crack abusers and drug treatment initiation: barriers and effects of a pretreatment intervention

African-American crack abusers and drug treatment initiation: barriers and effects of a pretreatment intervention

Background: Individual and sociocultural factors may pose significant barriers for drug abusers seeking treatment, particularly for African-American crack cocaine abusers. However, there is evidence that pretreatment interventions may reduce treatment initiation barriers. This study examined the effects of a pretreatment intervention designed to enhance treatment motivation, decrease crack use, and prepare crack abusers for treatment entry. Methods: Using street outreach, 443 African-American crack users were recruited in North Carolina and randomly assigned to either the pretreatment intervention or control group. Results: At 3-month follow-up, both groups significantly reduced their crack use but the intervention group participants were more likely to have initiated treatment. Conclusion: The intervention helped motivate change but structural barriers to treatment remained keeping actual admissions low. Policy makers may be interested in these pretreatment sites as an alternative to treatment for short term outcomes.

May 21, 2007

Drugs and Poverty – a literature review

Drugs and Poverty – a literature review

Literature review compiled by the Scottish Drugs Forum on the relationship between drug use and poverty. Keywords: poverty, social class, deprivation, deprived communities.

Too frightened to care? Accounts by district nurses working with clients who misuse substances

Too frightened to care? Accounts by district nurses working with clients who misuse substances

Health & Social Care in the Community Volume 15, Issue 3, Page 238-245, May 2007.
Abstract Drug misusers have complex health and social care needs, and experience considerable difficulties in accessing the assessment, care and treatment that they require. Despite the development of specialist services in many parts of the UK, substance...

May 18, 2007

Impact of welfare cheque issue days on a service for those intoxicated in public

Impact of welfare cheque issue days on a service for those intoxicated in public

In British Columbia (BC), the Ministry of Human Resources issues welfare cheques to eligible recipients monthly on the last Wednesday of each month. Previous studies have indicated that there are significant increases in hospital admission, ED admission, 911 calls and deaths shortly after the distribution of the monthly welfare cheques. The objective of this analysis was to rigorously examine the impact of welfare cheque issue dates on admission to the Sobering Unit (SU), a service for the publicly intoxicated, in Vancouver, Canada. Data on 1234 consecutive admissions to the SU over a 7-month period were assessed, and the average number of daily admissions on each of the 7 days of the welfare cheque issue week and similar weekdays in other weeks were compared. A Wilcoxon rank-sum test was performed for the comparisons. Our results showed that there were significant increases in the number of admissions on the 3 days starting with Welfare Wednesday compared to the similar weekdays in other weeks (Welfare Wednesday vs. other Wednesdays: 8.7 vs. 5.1, p =0.02; Welfare Thursdays vs. other Thursdays: 9.6 vs. 5.3, p =0.02; Welfare Fridays vs. other Fridays: 8.6 vs. 5.7, p =0.04). The demonstrated impact of welfare cheque issue dates is an important consideration for the re-design, staffing and resource allocation of services for withdrawal management and potentially for other services offered to this population.

May 17, 2007

The relationship between alcohol misuse and the drinks industry sponsorship of sporting activities

The relationship between alcohol misuse and the drinks industry sponsorship of sporting activities

Irish Gov't report on alcohol and sports sponsorship. Keywords: Ireland, Eire, alcohol, sport.

Achieving a high coverage – the challenge of controlling HIV spread in heroin users

Achieving a high coverage – the challenge of controlling HIV spread in heroin users

In China, the national plan to open 1000 methadone clinics over a five-year period provides a unique opportunity to assess the impacts of harm reduction in a country with concentrated HIV epidemic amongst heroin users. To track the progress of this public health response, data were collected from the first methadone clinic in Liuzhou, Guangxi, a province with a high HIV prevalence. In the first 15 months of its operation, a cumulative total of 488 heroin users, 86% of which male, had joined the programme. The first dose of methadone was given efficiently at a median of 2 days after registration. Of the 240 heroin users attending the clinic in August 2006, 61% took methadone for four days or more each week. The number of active methadone users, however, leveled off at around 170 after the first two months, despite the availability of capacity to deliver more services. The reasons for this observation are: firstly, the provision of one single service that may not be convenient to all heroin users; and secondly, concerns of heroin users who may feel insecure to come forward. As broad coverage is essential in ultimately reducing HIV risk, a low threshold approach is crucial, which should be supported by the removal of social obstacles and a refinement of the administrative procedures.

May 15, 2007

Binge Britain: Alcohol and the National Response. By Martin Plant and Moira Plant. Oxford University Press, Oxford, UK. 2006, 204pp., {pound}19.95. ISBN: 0-19-9299412

Binge Britain: Alcohol and the National Response. By Martin Plant and Moira Plant. Oxford University Press, Oxford, UK. 2006, 204pp., {pound}19.95. ISBN: 0-19-9299412

Naltrexone versus acamprosate in the treatment of alcohol dependence: a multi-crentre, randomized, double-blind, placebo controlled trial

Naltrexone versus acamprosate in the treatment of alcohol dependence: a multi-crentre, randomized, double-blind, placebo controlled trial

The results of this study support the efficacy of naltrexone in the relapse prevention of alcoholism amongst those with low levels of clinical depression and alcohol dependence severity. No effect of acamprosate was found.

May 14, 2007

Drug user involvement in treatment decisions

Drug user involvement in treatment decisions

Joseph Rowntree Foundation report offering guidance on implementing inclusion initiatives in drug treatment. Keywords: inclusion, client involvement, service users.

May 09, 2007

Therapeutic emails

Therapeutic emails

Background: In this paper, we show how counselors and psychologists can use emails for online management of substance abusers, including the anatomy and content of emails that clinicians should send substance abusers. Some investigators have attempted to determine if providing mental health services online is an efficacious delivery of treatment. The question of efficacy is an empirical issue that cannot be settled unless we are explicitly clear about the content and nature of online treatment. We believe that it is not the communications via internet that matters, but the content of these communications. The purpose of this paper is to provide the content of our online counseling services so others can duplicate the work and investigate its efficacy. Results: We have managed nearly 300 clients online for recovery from substance abuse. Treatment included individual counseling (motivational interviewing, cognitive-behavior therapy, relapse prevention assignments), participation in an electronic support group and the development of a recovery team. Our findings of success with these interventions are reported elsewhere. Our experience has led to development of a protocol of care that is described more fully in this paper. This protocol is based on stages of change and relapse prevention theories and follows a Motivational Interviewing method of counseling. Conclusion: The use of electronic media in providing mental health treatment remains controversial due to concerns about confidentiality, security and legal considerations. More research is needed to validate and generalize the use of online treatment for mental health problems. If researchers have to build on each others work, it is paramount that we share our protocols of care, as we have done in this paper.

May 08, 2007

Treating posttraumatic stress in motor vehicle accident survivors

Treating posttraumatic stress in motor vehicle accident survivors

Eric Kuhn, PhD; Edward J. Hickling, PsyD

May 07, 2007

Drama-based education to motivate participation in substance abuse prevention

Drama-based education to motivate participation in substance abuse prevention

Background: The substance abuse prevention goal of the theatre production "TUNNELS" was to provide community education on substance abuse to an audience in Durham, NC and surrounding communities. The education effort intended to increase awareness and understanding of the risk and protective factors associated with alcohol and other drug use, and to promote pro-active behaviors in substance abuse prevention within the adult community. It was hypothesized that community-based education via drama would change attitudes toward alcohol and substance abuse, and increase participation in family and community activities aimed at substance abuse prevention. Methods: A focus group comprised of educators, substance abuse researchers and local substance abuse counselors developed "life stories" of users of alcohol and other drugs and a local playwright incorporated these and other experiences into a series of six vignettes. The production was publicized throughout the Durham area, and 700 adults attending the play signed a consent form and completed the pre-play survey. The participant pool was restricted to those adults who completed both the time-1 and time-2 surveys and resided within Durham and surrounding communities. Paired comparisons of mean responses were analyzed using a paired sample two-tailed t-test. A telephone survey three months after the play assessed attitudes toward substance abuse as a disease, and whether the respondents had increased their participation in prevention activities including discussions of the play with others. Results: Viewing the play increased the knowledge base of participants regarding substance abuse as a disease, even though the audience demonstrated an appreciation of risk and protective factors prior to attending the performance. In the pre-play survey, participants indicated a strong opinion that parental involvement in teen life was important, and therefore this was not increased as a result of viewing the play. It was found that the drama increased intent to participate in substance abuse prevention activities at home and in the community. Follow-up surveys performed three months after the performance indicated that participants had discussed the play with others and had increased their participation in substance abuse prevention activities, particularly regarding donations of money. Conclusion: Drama incorporates a component of emotional response to the informational content, and the combination of emotion and information works together to promote individual intentions to become more involved in family and community prevention activities. This study demonstrates the efficacy of drama as a mechanism to educate and motivate. Support for this mechanism is warranted at the level of state, local community, school district, and faith-based and community organizations.

May 04, 2007

Use of crystal methamphetamine among gay men in London

Use of crystal methamphetamine among gay men in London

Among gay men in London surveyed in clinics, approximately one in ten reported using crystal methamphetamine in the preivous 12 months. Most men used it infrequently. There is no evidence of increasing use of crystal meth between 2003 and 2005.

A randomized controlled pilot study of motivational interviewing for patients with psychotic and drug use disorders

A randomized controlled pilot study of motivational interviewing for patients with psychotic and drug use disorders

These findings suggest that motivational interviewing may not work equally well for all types of psychotic disordered dually diagnosed patients.

THE INFLUENCE OF PRODUCT PACKAGING ON YOUNG PEOPLE'S PALATABILITY RATING FOR RTDs AND OTHER ALCOHOLIC BEVERAGES

THE INFLUENCE OF PRODUCT PACKAGING ON YOUNG PEOPLE'S PALATABILITY RATING FOR RTDs AND OTHER ALCOHOLIC BEVERAGES

 

Aims: To investigate the influence of product packaging of ready to drink (RTD), or pre-mixed drinks, and other alcoholic and non-alcoholic beverages on the palatability ratings of adolescents and adults. Respondents were interviewed at their own schools or a campus of the University of NSW. The experiment tested palatability ratings in blind and non-blind conditions with a selection of 12- to 30-year-old Australians (140 adolescents and 210 adults) from seven private schools across NSW and students from the University of NSW and Macquarie University. Methods: Beverage palatability was measured utilizing an interval ratio scale from 1 to 7 before and after packaging was presented. Views on whether the beverage packaging was designed to appeal to the participant were also analysed. Results: In general, the alcoholic beverage packaging was thought to be designed to appeal more to adults and palatability ratings significantly increased in the non-blind conditions. In contrast, the Bacardi Breezer packaging was especially palatable to younger participants. Conclusions: Although most alcoholic beverage packaging was not of particular appeal to adolescents, some RTD beverages may be appealing more to adolescents. Unlike other alcoholic products, the difference in palatability ratings for the Bacardi Breezer, from blind to non-blind conditions, was greater for younger participants.

Treating Alcohol and Drug Problems in Psychotherapy Practice. By Arnold M. Washton and Joane Zweben. Guilford Press, NY. 2006, 312pp., {pound}25. ISBN: 9781572300774

Treating Alcohol and Drug Problems in Psychotherapy Practice. By Arnold M. Washton and Joane Zweben. Guilford Press, NY. 2006, 312pp., {pound}25. ISBN: 9781572300774

THE RELATIONSHIP BETWEEN EXPOSURE TO ALCOHOL ADVERTISING IN STORES, OWNING ALCOHOL PROMOTIONAL ITEMS, AND ADOLESCENT ALCOHOL USE

THE RELATIONSHIP BETWEEN EXPOSURE TO ALCOHOL ADVERTISING IN STORES, OWNING ALCOHOL PROMOTIONAL ITEMS, AND ADOLESCENT ALCOHOL USE


Aim: This paper describes adolescents' exposure to alcohol advertising in stores and to alcohol-branded promotional items and their association with self-reported drinking. Methods: A cross-sectional survey was administered in non-tracked required courses to sixth, seventh, and eighth graders (n = 2125) in three California middle schools. Logistic regressions compared the odds of ever (vs. never) drinking and current (vs. ever) drinking after controlling for psychosocial and other risk factors for adolescent alcohol use. Results: Two-thirds of middle school students reported at least weekly visits to liquor, convenience, or small grocery stores where alcohol advertising is widespread. Such exposure was associated with higher odds of ever drinking, but was not associated with current drinking. One-fifth of students reported owning at least one alcohol promotional item. These students were three times more likely to have ever tried drinking and 1.5 times more likely to report current drinking than students without such items. Conclusions: This study provides clear evidence of an association of adolescent drinking with weekly exposure to alcohol advertising in stores and with ownership of alcohol promotional items. Given their potential influence on adolescent drinking behaviour, retail ads, and promotional items for alcohol deserve further study.



Warning About Abuse of Benzylpiperazine

Warning About Abuse of Benzylpiperazine

Benzylpiperazine, a chemical cousin of ecstasy, could emerge as a new drug of abuse, according to a leading toxicologist.


Impact of parental history of substance use disorders on the clinical course of anxiety disorders

Impact of parental history of substance use disorders on the clinical course of anxiety disorders

Background: Among the psychological difficulties seen in children of parents with substance use problems, the anxiety disorders are among the most chronic conditions. Although children of alcoholic parents often struggle with the effects of parental substance use problems long into adulthood, empirical investigations of the influence of parental substance use disorders on the course of anxiety disorders in adult offspring are rare. The purpose of this study was to examine prospectively the relationship between parental substance use disorders and the course of anxiety disorders in adulthood over the course of 12 years. Methods: Data on 618 subjects were derived from the Harvard/Brown Anxiety Research Project (HARP), a longitudinal naturalistic investigation of the clinical course of multiple anxiety disorders. Kaplan-Meier survival estimates were used to calculate probabilities of time to anxiety disorder remission and relapse. Proportional hazards regressions were conducted to determine whether the likelihood of remission and relapse for specific anxiety disorders was lower for those who had a history of parental substance use disorders than for individuals without this parental history. Results: Adults with a history of parental substance use disorders were significantly more likely to be divorced and to have a high school level of education. History of parental substance use disorder was a significant predictor of relapse of social phobia and panic disorders. Conclusions: These findings provide compelling evidence that adult children of parents with substance use disorders are more likely to have relapses of social phobia and panic disorders. Clinicians who treat adults with anxiety disorders should assess parental substance use disorders and dependence histories. Such information may facilitate treatment planning with regards to their patients level of vulnerability to perceive scrutiny by others in social situations, and ability to maintain a long-term panic-free state.


February 28, 2007

Professional Perspectives On Addiction Medicine

Professional Perspectives On Addiction Medicine

Comprehensive handbook on methadone maintenance treatment for opioid addiction. Keywords: methadone, maintenance, substitute prescribing.

February 22, 2007

The psychological science of addiction

The psychological science of addiction

Addiction Volume 0, Issue 0, Page ???-???.
ABSTRACT Aim  To discuss the contributions and future course of the psychological science of addiction. Background  The psychology of addiction includes a tremendous range of scientific activity, from the basic experimental laboratory through increasingly...


Treatment For Homeless Youth Pays Off In Long Run, Study Finds

Treatment For Homeless Youth Pays Off In Long Run, Study Finds

One of the few studies examining methods to help homeless youth found that a comprehensive intervention program can indeed dramatically improve their life situation.The six-month study of homeless youth in Albuquerque found that teens who completed the program significantly reduced their substance abuse and depression and increased their social stability, including the number of days living off the streets, compared to those who received standard treatment. [click link for full article]


February 21, 2007

Effects of Conditioned Reward and Nonreward Cues on the Heart Rate Response to Alcohol Intoxication in Male Social Drinkers

Effects of Conditioned Reward and Nonreward Cues on the Heart Rate Response to Alcohol Intoxication in Male Social Drinkers

Alcoholism: Clinical and Experimental Research Volume 0, Issue 0, Page ???-???.
Background: An exaggerated heart rate (HR) increase following alcohol intoxication has been suggested to reflect sensitivity to alcohol-induced reward. The goal of this study is to verify whether pairing alcohol ingestion with conditioned reward and nonr...


Women And Recovery From Alcoholism

Women And Recovery From Alcoholism

PhD candidate Ms Janice Withnall, from the UWS School of Education, is carrying out the project in a bid to better understand the experiences of women who have successfully stopped drinking.National statistics show that alcohol-related illness hospitalises 95,000 Australians a year. Of that group, 7 per cent are women who are alcohol dependent. [click link for full article]


A Matter of Substance?

A Matter of Substance?

Aberlour Trust report examining the situation of chilkdren in families where there is alcohol or drugs misuse. Keywords: drug-using parents, children, young people, family.


February 20, 2007

Circles of Support and Accountability: Engaging Community Volunteers in the Management of High-Risk Sexual Offenders

Circles of Support and Accountability: Engaging Community Volunteers in the Management of High-Risk Sexual Offenders

The Howard Journal of Criminal Justice Volume 46, Issue 1, Page 1-15, Feb 2007.
Abstract: The release to the community of a sexual offender is frequently accompanied by intense coverage in the news media. Too often, the type of coverage these releases receive serves only to force many offenders into hiding or out of one community an...


EARLY DRINKING AND THE DEVELOPMENT OF ALCOHOLISM: A COMMENTARY ON SARTOR ET AL. (2007)

EARLY DRINKING AND THE DEVELOPMENT OF ALCOHOLISM: A COMMENTARY ON SARTOR ET AL. (2007)

Addiction Volume 102, Issue 2, Page 188-189, Feb 2007.


Stress-Induced and Alcohol Cue-Induced Craving in Recently Abstinent Alcohol-Dependent Individuals

Stress-Induced and Alcohol Cue-Induced Craving in Recently Abstinent Alcohol-Dependent Individuals

Alcoholism: Clinical and Experimental Research Volume 0, Issue 0, Page ???-???.
Background: Research has shown that exposure to stress/negative affect and to alcohol cues can each increase alcohol craving and relapse susceptibility in alcohol-dependent individuals. However, whether the emotional and physiological states associated w...


Social Gradients In Binge Drinking And Abstaining In British Women

Social Gradients In Binge Drinking And Abstaining In British Women

British women's binge drinking is clearly defined by their age and education, suggests a large, long term study in the Journal of Epidemiology and Community Health.Educated women binge drink in their 20s, but curb their habits by their 40s. But the reverse is true of women with little education, whose binge drinking is more likely to take off in their 40s, shows the research. [click link for full article]


Gambling Treatment MUST Be Available On The NHS, Say Doctors

Gambling Treatment MUST Be Available On The NHS, Say Doctors

In its hard-hitting report, Gambling addiction and its treatment within the NHS, released recently, the BMA is calling for gambling to be a recognised addiction that requires treatment on the NHS.This recommendation is part of a tough set of proposals aimed at helping healthcare professionals deal effectively with the growing problem of gambling addiction in the UK. The report is timely given the 2005 Gambling Act is due to come into force this September. [click link for full article]


Liver transplant and hepatitis C in methadone maintenance therapy: a case report

Liver transplant and hepatitis C in methadone maintenance therapy: a case report

Methadone maintenance therapy for the treatment of opioid dependence continues to carry a social stigma. Until recently, patients on methadone were not considered for liver transplantation. We describe the first case of a patient on methadone who received a liver transplant for end stage liver disease and was successfully treated for recurrent hepatitis C. More than five years post transplant and three years post viral clearance, the patient continues to do well and is stable on low-dose methadone. This case emphasizes the need to reconsider the non-evidence based policy adopted by transplant centers that require methadone maintenance therapy patients to stop methadone prior to consideration for transplant evaluation.


February 19, 2007

An Introduction to Family Therapy: Systemic Theory and Practice by Rudi Dallos and Ros Draper

An Introduction to Family Therapy: Systemic Theory and Practice by Rudi Dallos and Ros Draper

Journal of Family Therapy Volume 29, Issue 1, Page 91-92, Feb 2007.


February 16, 2007

Risk-taking and the adolescent brain: who is at risk?

Risk-taking and the adolescent brain: who is at risk?

Developmental Science Volume 10, Issue 2, Page F8-F14, Mar 2007.
Abstract Relative to other ages, adolescence is described as a period of increased impulsive and risk-taking behavior that can lead to fatal outcomes (suicide, substance abuse, HIV, accidents, etc.). This study was designed to examine neural correlates of...


February 15, 2007

Methadone-exposed newborn infants: outcome after alterations to a service for mothers and infants

Methadone-exposed newborn infants: outcome after alterations to a service for mothers and infants

Child: Care, Health and Development Volume 33, Issue 2, Page 206-212, Mar 2007.
Abstract Objective To evaluate the impact of a shared care approach in clinical management with a drug liaison midwife (DLM) service for mothers and infants established in 1995–1996 in an inner city area and to address the problem of congenital abnormali...


February 14, 2007

Treatment of polydrug-using opiate dependents during withdrawal: towards a standardisation of treatment

Treatment of polydrug-using opiate dependents during withdrawal: towards a standardisation of treatment

Detoxification study which compared the short-time efficacy of a standardised regimen comprising 6 days Buprenorphine and 10 days Valproate to a control group who took a 10-day traditional Clonidine/Carbamazepine regimen.


Heavy Drinking Takes Excessive Toll On Women With Hepatitis C

Heavy Drinking Takes Excessive Toll On Women With Hepatitis C

Women tend to survive longer than men if infected with the liver-destroying hepatitis C virus (HCV) -- but if they drink heavily, that survival advantage completely disappears, according to a new study."Previous studies indicated that alcohol use is a risk factor for HCV disease progression, but they seldom examined the effect on women and men separately," said lead author Chiung Chen. "Even fewer studies were able to examine the effect of alcohol on HCV mortality. [click link for full article]


Toward a New Recovery Movement

Toward a New Recovery Movement

William White's history of addiction treatment. Keywords: history, alcoholism, treatment, theory.


Patient Level Opioid Risk Management

Patient Level Opioid Risk Management

Technical guide to the use of opioids in the management of pain. Keywords: opioids, pain, clinical management.


Safer Management of Controlled Drugs

Safer Management of Controlled Drugs

Department of Health (UK) advice on control and security for controlled drugs. Keywords: pharmacists, chemists, storage, management, controlled drugs.


Drinking: adults’ behaviour and knowledge in 2006

Drinking: adults’ behaviour and knowledge in 2006

A report on research using the ONS Omnibus Survey produced by the Office for National Statistics on behalf of the Information Centre for Health and Social Care. Keywords: drinking patterns, consumption, alcohol misuse, prevention, education.


February 13, 2007

Childhood Abuse Predicates Health Problems

Childhood Abuse Predicates Health Problems

Childhood Abuse Predicates Health Problems


Meth and psychosis

Meth and psychosis

February 12, 2007

Naltrexone Implants Don't Eliminate Overdose Risk

Naltrexone Implants Don't Eliminate Overdose Risk

Implants that deliver time-released doses of the anti-addiction medication naltrexone have been touted for preventing drug overdoses, but Australian researchers have found at least five fatal overdoses among implant patients.


Methadone in pregnancy: treatment retention and neonatal outcomes

Methadone in pregnancy: treatment retention and neonatal outcomes

Addiction Volume 102, Issue 2, Page 264-270, Feb 2007.
ABSTRACT Aim  To examine the association between retention in methadone treatment during pregnancy and key neonatal outcomes. Design  Client data from the New South Wales Pharmaceutical Drugs of Addiction System was linked to birth information from the NS...


Does marijuana contribute to psychotic illness?

Does marijuana contribute to psychotic illness?

Joseph M. Rey, MD, PhD


February 09, 2007

Interferon alpha therapy for hepatitis C: Treatment completion and response rates among patients with substance use disorders

Interferon alpha therapy for hepatitis C: Treatment completion and response rates among patients with substance use disorders

Background: Individuals with substance use disorders (SUDs) are at increased risk for hepatitis C viral infection (HCV), and few studies have explored their treatment responses empirically. The objective of this study was to assess interferon alpha therapy (IFN) completion and response rates among patients with HCV who had a history of comorbid SUDs. More data is needed to inform treatment strategies and guidelines for these patients. Using a medical record database, information was retrospectively collected on 307,437 veterans seen in the Veterans Integrated Service Network 20 (VISN 20) of the Veterans Healthcare Administration (VHA) between 1998 and 2003. For patients treated with any type of IFN (including regular or pegylated IFN) or combination therapy (IFN and ribavirin) who had a known HCV genotype, IFN completion and response rates were compared among patients with a history of SUD (SUD+ Group) and patients without a history of SUD (SUD- Group). Results: Odds ratio analyses revealed that compared with the SUD- Group, the SUD+ Group was equally likely to complete IFN therapy if they had genotypes 2 and 3 (73.1% vs. 68.0%), and if they had genotypes 1 and 4 (39.5% vs. 39.9%). Within the sample of all patients who began IFN therapy, the SUD- and SUD+ groups were similarly likely to achieve an end of treatment response (genotypes 2 and 3, 52.8% vs. 54.3%; genotypes 1 and 4, 24.5% vs. 24.8%) and a sustained viral response (genotypes 2 and 3, 42.6% vs. 41.1%; genotypes 1 and 4: 16.0% vs. 22.3%). Conclusions: Individuals with and without a history of SUD responded to antiviral therapy for HCV at similar rates. Collectively, these findings suggest that patients who have co-morbid SUD and HCV diagnoses can successfully complete a course of antiviral therapy.


February 08, 2007

Limits of care: What events can you prevent?

Limits of care: What events can you prevent?

Jon E. Grant, JD, MD, MPH


Playing SOCA with drug policy?

Playing SOCA with drug policy?

 

SOCA, the new Serious Organised Crime Agency, launched by Tony Blair with some considerable fanfare in April last year seems to be running into problems even before it's first year is up. At the launch The prime minister told us that from now on life would be "hell" for "criminal Mr Bigs", and the previous Home Secretary announced that he was “sending the organised criminal underworld a clear message: be afraid". (Telegraph comment piece)




Blair launches SOCA, promising 'Hell' for 'Mr Big'


But two reports on Channel Four News last week suggested that any honeymoon period is well and truly over, and that Mr Big may not be quite as afraid as was hoped. So what's it all about and why have things apparently gone pear shaped so quickly? The news reports, which included interviews with disgruntled SOCA staff and various leaked emails, suggested bureaucracy and management issues, low morale and 'loopholes' that meant large numbers of drug seizures were not being followed up, attracting the ire of Police Federation amongst others.

But the problem with SOCA (I am only talking about the drugs side of their work here) is not primarily and internal one of incompetence or organisational strategy. The real problem is because of the terrible truth: the better SOCA do their job, the worse things will get. Supply side drug controls do not and cannot prevent drugs from reaching markets where sufficient demand exists. The best they can achieve is to further inflate drug prices, driving low income problematic users into ever larger volumes of offending to support their habits and attracting ever more violent criminals to control the profits offered up by prohbition. As we shall see, this is no secret to ministers.

SOCA was established last April following a merger of the National Crime Squad, the National Criminal Intelligence Service, and sections of HM Revenue and Customs (HMRC) and the Immigration Service. The new entity has a £400+ million a year budget, and organised crime involvement with the drugs is the most significant focus of their work. According the SOCA website:

Trafficking in heroin and cocaine, particularly crack cocaine, poses the greatest single threat to the UK in terms of the scale of serious organised criminal involvement, the illegal proceeds secured and the overall harm caused.

Home Office estimates put the harm caused by Class A drugs at around £13bn a year. This largely arises from the profits from sales, the crimes addicts commit to fund their habit, and the damage caused to family life and communities, as well as from costs to addicts' health
.

As a brief aside, the above isn't a summary of the information of the SOCA's drug related activities on their website – that's all of it.

Anyway, if the organisation seems to be running into trouble this certainly isn't the fault of its core staff – many of whom, according to the Times, are apparently now trying to leave because of the organisational malaise and a desire to do some real hands on police work. I have met SOCA staff at various conferences and seminars and their professionalism and commitment to tackling organised crime isn't in question.

No, if there is a problem it is primarily the politics behind the organisation, that casts a shadow over everything it does. The backdrop to the establishment of SOCA is a 10 year drug strategy that, as it approaches its end, has failed in quite spectacular style to achieve its targets on reducing Class A drug supply and use (remember that 50% reduction in class A drug use/availability by 2008?). This failure is combined with a political climate of macho law and order posturing and one-up-manship between the major political parties, characterised by tough talking rhetoric that is heavily dictated by a tabloid agenda.

Drug policy under this Government (and to be fair, previous ones aswell) has been dominated by politics, remaining, for the most part, resolutely un-bothered by rational evidence based policy making. As drug supply, drug use, drug crime, and overall drug harm have continued to rise, the Government, rather than consider a change of approach or progressive policy alternatives, has defaulted to tough talking spin and bluster:

'Tough' new targets are announced as the old ones are missed and quietly retired, usually made as part of an updated strategy, from a newly re-named Drug Strategy Unit/Directorate/Wotsit, after a relocation to a new ministry, or by a tough new 'bruiser' Home Secretary – because obviously that's going to make a massive difference.

'Tough' new legislation is passed, like 2005's ill-thought out Drugs Act, which no-one in the drugs field wanted or asked for (the only welcome clause being the repeal of reforms to section 8 of the MDA, from the Government's previous ill thought out get-tough (sp)initiative). Much of it – like clause 2 of the Drugs Act – is never likely to be commenced because it is frankly a load of rubbish. I use the term advisedly as the biggest Drugs Act nerd on the planet outside of the poor unfortunates at the Home Office who had to draft it.

'Tough' announcements that grab a few headlines but never actually come to fruition because they are impractical, unethical, or occasionally illegal. Consider for example random drug testing in schools (announced in a Tony Blair exclusive interview in the News of the World), or the equally idiotic drugs sniffer dogs in schools, both going the same way (nowhere) as mandatory minimums, three strikes you're out, and all that other disastrous US-style 'war on drugs' nonsense.

'Tough' new appointments are made – The Drug Czar, a tough cop who looks a bit like Jack Palance, modelled on his ass-kickin' US counterpart, who is then unceremoniously dumped a couple of years later - a straw man for a doomed enforcement-led drug strategy he had no hope of salvaging.

And on and on it goes. There's a pattern here. Drug policy has been all about the big announcements, the new stuff – the process. Its all about the future, about turning the corner, about the upcoming breakthrough, about being tough. Its never about the outcomes.

For the simple reason – obvious to anyone not in a sensory deprivation tank for the past decade - that the outcomes are all dreadful.

Worse than dreadful – they are the opposite of what they were supposed to be. Class A drug use, (in particular the problematic kind that we should genuinely be concerned about), has gone up since 1997. A lot – including the crack 'epidemic' that all that toughness manifestly failed to prevent. Drugs are cheaper and more available than they have ever been. By a considerable margin. Attempts to control drug supply are a joke, and a pretty poor return on the £20 billion or so that has been hosed into drug policy enforcement over the past decade. And let us not forget that of the £13 billion a year of drug related harm that SOCA mentions on its otherwise totally un-infomative website, 88% of which is crime costs, and 95% of that being crime committed by addicts to support their habits. ie created by enforcement. ie costs of prohibition.

So come 2002 and Tony Blair is looking down the barrel of a drug policy disaster, a ten year strategy dramatically not doing what is was supposed to, and various groups including the Police Foundation and the Home Affairs Select Committee pointing out this fact very eloquently and publicly. At this point he called upon the top boys from his personal policy think tank – the Number Ten Strategy Unit – and they produced a devastating 114 page analysis of UK drug policy that shows with crystal clarity that supply side enforcement cannot ever work and actually creates huge collateral damage in the form of that £13billion or so a year in crime costs (they actually put it at £16 billion).

The No 10 report (presented to ministers and then supressed until FOI pressure and leaks brought it into the public domain) notes that:

“UK importers and suppliers make enough profit to absorb the modest cost of drug seizures” (p.82)

“The long term decline in the real price of drugs, against a backdrop of rising consumption, indicates that an ample supply of heroin and cocaine has been reaching the UK market”(p.80)

“Despite seizures, real prices for heroin and cocaine in the UK have halved over the last ten years”(p.91)

“Over the past 10-15 years, despite interventions at every point in the supply chain, cocaine and heroin consumption has been rising, prices falling and drugs have continued to reach users. Government interventions against the drug business are a cost of business, rather than a substantive threat to the industry's viability.” (p.94)


The report goes on to demonstrate how this crime will always be created by the underlying economics of the completely deregulated illegal drug market. When increasing numbers of users have to pay street prices grossly inflated by prohibition, the exploding levels of crime described in the report are inevitable:

“The high profitability of the drugs business is derived from a premium for taking on risk, as well as from the willingness of drug users to pay high prices” (p.66)

“profit margins for traffickers can be even higher than those of luxury goods companies” – (cites Gucci as an example) (p.69)


The report then shows that even if supply side interventions (exactly what SOCA are now involved in) were more successful, the result would be increased prices that could force addicts to commit more crime to support their habits.

“There is no evidence to suggest that law enforcement can create such droughts” (p.102
)

[but even if they could…..]

“price increases may even increase overall harm, as determined users commit more crime to fund their habit and more than offset the reduction in crime from lapsed users”(p.99)

John Birt, 'blue skies' thinker and drug policy non-expert, then took that analysis and, in phase two of the Strategy Unit report, tried to come up with some sensible policy responses. Ignoring the analysis that enforcement was counter-productive and creating many of the very problems it was intended to eliminate (presumably because to not ignore it took policy in a direction he found politically unpalatable), he instead devised a repressive programme for shovelling ever greater numbers of drug using offenders into enforced abstinence-based 'treatment' as a way of reducing drug related crime (which formed the basis of the non-sensible Drugs Act 2005).

But no one really thought this was going to be the magic bullet, not even Birt, and besides, treatment isn't much of political crowd pleaser. And so it seemed the stage was set for some more tough new initiatives – yet more process announcements that would delay the reckoning a bit longer. This time though they needed something really big and seriously tough: we obviously needed our very own FBI. And that was what we got, £400million a year's worth, complete with its own futuristic new logo, featuring a big scary cat with mean looking claws striding the globe.




SOCA logo





The Eye of Thundera - Thundercats insignia

So whether SOCA is functioning better or worse than the various agencies it replaces isn't really the point (that really is just a process consideration). If anything the worse they perform the better. But even if SOCA was running like a well oiled military machine, arresting baddies like there was no tommorow (and the 'Mr Bigs' thought the daft thundercats logo was really intimidating), it still wouldn't save them from inevitable failure because however you dress it up, supply enforcement doesn't work, it just makes things worse. Drug seizures, however dramatic, don't stop drugs reaching their markets and arresting violent drug dealing hoodlums and smashing drug crime syndicates just creates a vacancy for the next generation of gangsters, all to keen to make a killing from prohibition. SOCA is an organisation whose drugs brief is set up to fail, and that must be pretty demoralising.


Overdose prevention for injection drug users: Lessons learned from naloxone training and distribution programs in New York City

Overdose prevention for injection drug users: Lessons learned from naloxone training and distribution programs in New York City

Background: Fatal heroin overdose is a significant cause of mortality for injection drug users (IDUs). Many of these deaths are preventable because opiate overdoses can be quickly and safely reversed through the injection of Naloxone [brand name Narcan], a prescription drug used to revive persons who have overdosed on heroin or other opioids. Currently, in several cities in the United States, drug users are being trained in naloxone administration and given naloxone for immediate and successful reversals of opiate overdoses. There has been very little formal description of the challenges faced in the development and implementation of large-scale IDU naloxone administration training and distribution programs and the lessons learned during this process. Methods: During a one year period, over 1,000 participants were trained in SKOOP (Skills and Knowledge on Opiate Prevention) and received a prescription for naloxone by a medical doctor on site at a syringe exchange program (SEP) in New York City. Participants in SKOOP were over the age of 18, current participants of SEPs, and current or former drug users. We present details about program design and lessons learned during the development and implementation of SKOOP. Lessons learned described in the manuscript are collectively articulated by the evaluators and implementers of the project. Results: There were six primary challenges and lessons learned in developing, implementing, and evaluating SKOOP. These include a) political climate surrounding naloxone distribution; b) extant prescription drug laws; c) initial low levels of recruitment into the program; d) development of participant appropriate training methodology; e) challenges in the design of a suitable formal evaluation; and f) evolution of program response to naloxone. Conclusions: Other naloxone distribution programs may anticipate similar challenges to SKOOP and we identify mechanisms to address them. Strategies include being flexible in program planning and implementation, developing evaluation instruments for feasibility and simplicity, and responding to and incorporating feedback from participants.


Excessive Drinking, Not Alcoholism, May Lead To Most Alcohol-Related Problems

Excessive Drinking, Not Alcoholism, May Lead To Most Alcohol-Related Problems

* Many people assume that most people who drink to excess are probably alcoholics. * A recent survey of 4,761 New Mexico adults found that while 16.5 percent drank alcohol in excess of national guidelines, only 1.8 percent met criteria for alcohol dependence. * This suggests that a majority of persons at risk for alcohol-related problems are not alcohol dependent. [click link for full article]


ALCOHOL POLICY: WHO SHOULD SIT AT THE TABLE?

ALCOHOL POLICY: WHO SHOULD SIT AT THE TABLE?

'Moral panic' threat to children of drug addicts

'Moral panic' threat to children of drug addicts

HUNDREDS of children whose parents are drug addicts face the risk of being taken into care because of a "moral panic" over the issue, Scotland's drug and alcohol tsar has warned.


What five cigarettes a day does to your arteries

What five cigarettes a day does to your arteries

A new scan at the University College London is showing the damage that a five-a-day cigarette habit can do to an otherwise healthy person's arteries. Here KATHRYN KNIGHT tries it out